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Non-classical MEKs: A review of MEK3-7 inhibitors

Non-classical MEKs: A review of MEK3-7 inhibitors

Translational Chemistry

Kwong, A. J.; Scheidt, K. A.* Bioorg. Med. Chem. Lett. 2020, 30, 127203.
Targeted Covalent Inhibition of Telomerase

Targeted Covalent Inhibition of Telomerase

Translational Chemistry

Betori, R. C.; Liu, Y.; Mishra, R. K.; Cohen, S. B.; Kron, S. J.; Scheidt, K. A.* ACS Chem. Biol. 2020, 15, 706-717.
Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors

Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors

Translational Chemistry

Deibler, K. K.; Schiltz, G. E.; Clutter, M. R.; Mishra, R. K.; Vagadia, P.P.; O’Connor, M.; George, M. D.; Gordon, R.; Fowler, G.; Bergan, R.; Scheidt, K. A.* Chem. Med. Chem. 2019, 14, 615-620. Featured in: Special Collection on Cancer Research (Hot Topics 2020,...
Precision therapeutic targeting of human cancer cell motility

Precision therapeutic targeting of human cancer cell motility

Translational Chemistry

Xu, L.; Gordon, R.; Farmer, R.; Pattanayak, A.; Binkowski, A.; Huang, X.; Avram, M.; Krishna, S.; Voll, E.; Pavese, J.; Chavez, J.; Bruce, J.; Mazar, A.; Nibbs, A.; Anderson, W.; Li, L.; Jovanovic, B.; Pruell, S.; Valsecchi, M.; Francia, G.; Betori, R. Scheidt, K.;...
A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family

A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family

Translational Chemistry

Deibler, K. K.; Mishra, R.K.; Clutter, M. R.; Antanasijevic, A. Bergan, R.; Caffrey, M.; Scheidt, K. A.* ACS Chem. Biol. 2017, 12, 1245-1256.
Virtual High-Throughput Screening To Identify Novel Activin Antagonists

Virtual High-Throughput Screening To Identify Novel Activin Antagonists

Translational Chemistry

Zhu, J.; Mishra, R. K.; Schiltz, G. E.; Makanji, Y.; Scheidt, K. A.; Mazar, A. P.; Woodruff, T. K. J. Med. Chem. 2015, 58 (14), 5637-5648.
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