Driving Research Forward
We are a diverse team of scientists seeking to advance fundamental knowledge and impact society.
About Our Lab
Our collaborative and interdisciplinary program is at the forefront of the discovery of new catalytic reactions and their applications in medicine.
Specifically, we have pioneered the use of small organic molecules as catalysts in a multitude of high value chemical transformations. These processes provide new avenues for molecular construction and offer sustainable advantages to established transition metal catalyzed approaches. In the realm of therapeutic translational science and chemical biology, we are creating new routes to natural products and related analogs with promising activities against cancer and central nervous system disorders that allow us to study the key molecular processes involved in these complex biological systems.
We greatly appreciate the past and current support from government and private agencies for our research and training.
The Scheidt lab has a strong emphasis on creative problem-solving and a commitment to mentorship.
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Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization
Liu, Y.; Betori, R. C.; Pagacz, J.; Frost, G. B.; Efimova, E. V.; Wu, D.; Wolfgeher, D. J.; Bryan, T. M.; Cohen, S. B.; Scheidt, K. A.; Kron, S. J.* Cell Chem. Biol. 2022, DOI: 10.1016/j.chembiol.2022.09.002
McCollum, M. M.; Larmore, M.; Ishihara, S.; Ng, L. C. T.; Kimura, L. F.; Guadarrama, E.; Ta, M. C.; Vien, T. N.; Frost, G. B.; Scheidt, K. A.; Miller, R. E.; DeCaen, P. G.* Cell Rep. 2022, DOI: 10.1016/j.celrep.2022.111248
Bay, A. V.; Farnam, E. J.; Scheidt, K. A.* J. Am. Chem. Soc. 2022, DOI: 10.1021/jacs.1c13105