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- Novel Thermoplastic Polyhydroxyurethane Elastomers as Effective Damping Materials over Broad Temperature Ranges
- Rational Design, Optimization, and Biological Evaluation of Novel MEK4 Inhibitors against Pancreatic Adenocarcinoma
- Tuning Nanophase Separation Behavior in Segmented Polyhydroxyurethane via Judicious Choice of Soft Segment
- Ferrocene-Based Planar Chiral Imidazopyridinium Salts for Catalysis
- Enantioselective Syntheses of Heteroyohimbine Natural Products: A Unified Approach through Cooperative Catalysis
- Cooperative Catalysis and Activation with N-Heterocyclic Carbenes
- Cooperative Catalysis of Cyclic Carbonate Ring Opening: Application Towards Non-Isocyanate Polyurethane Materials
- Discovery of 1,3,4-oxidiazole scaffold compounds as inhibitors of superoxide dismutase expression
- N-Heterocyclic Carbene-Catalyzed Oxidations
- Virtual High-Throughput Screening To Identify Novel Activin Antagonists
- Emerging Roles of in Situ Generated Quinone Methides in Metal-Free Catalysis
- Lewis Acid Activation of a Hydrogen Bond Donor Metal–Organic Framework for Catalysis
- Pyranone Natural Products as Inspirations for Catalytic Reaction Discovery and Development
- Enantioselective β-Protonation by a Cooperative Catalysis Strategy
- Catalytic Kinetic Resolution of a Dynamic Racemate: Highly Stereoselective β-Lactone Formation by N-Heterocyclic Carbene Catalysis
- Catalytic Enantioselective Synthesis of 2-Aryl Chromenes
- Azaindole synthesis through dual activation catalysis with N-heterocyclic carbenes
- MEK4 Function, Genistein Treatment, and Invasion of Human Prostate Cancer Cells
- 5-(1,1-dimethylethyl)-5,6-dihydro-2-phenyl-(5S)-oxazolo[2,3-c]-1,2,4-triazolium tetrafluoroborate
- A Biocatalytic Route to Highly Enantioenriched β-Hydroxydioxinones
- A Cooperative Ternary Catalysis System for Asymmetric Lactonizations of α-Ketoesters
- Conjugate Additions of Amines to Maleimides via Cooperative Catalysis
- Prins-Type Macrocyclizations as an Efficient Ring-Closing Strategy in Natural Product Synthesis
- Lewis Acid Activated Synthesis of Highly Substituted Cyclopentanes by the N-Heterocyclic Carbene Catalyzed Addition of Homoenolate Equivalents to Unsaturated Ketoesters
- Enantioselective Syntheses of Yohimbine Alkaloids: Proving Grounds for New Catalytic Transformations
- Synthesis of (–)-Okilactomycin by a Prins-Type Fragment-Assembly Strategy
- Enantioselective Synthesis of (–)-Exiguolide by Iterative Stereoselective Dioxinone-Directed Prins Cyclizations
- Combined Photoredox and Carbene Catalysis for the Synthesis of γ-Aryloxy Ketones
- An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones
- Catalytic Dynamic Kinetic Resolutions with N-Heterocyclic Carbenes: Asymmetric Synthesis of Highly Substituted β-Lactones
- A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis
- A Cascade Isomerization/Prins Strategy through Iridium(III)/Brønsted Acid Cooperative Catalysis
- Enantioselective N-Heterocyclic Carbene Catalyzed Annulation Reactions with Imidazolidinones
- A Cooperative N-Heterocyclic Carbene/Chiral Phosphate Catalysis System for Allenolate Annulations
- N-Heterocyclic-Carbene-Catalyzed Synthesis of 2-Aryl Indoles
- A Carbene Catalysis Strategy for the Synthesis of Protoilludane Natural Products
- Asymmetric Methods for the Synthesis of Flavanones, Chromanones, and Azaflavanones
- (S)-5-Benzyl-2-mesityl-6,6-dimethyl-6,8-dihydro-5H-[1,2,4]triazolo[3,4-C][1,4]oxazin-2-ium tetrafluoroborate
- Copper(I)-Catalyzed Disilylation of Alkylidene Malonates Employing a Lewis Base Activation Strategy
- The Thiazolium-Catalyzed Sila-Stetter Reaction: Conjugate Addition of Acylsilanes to Unsaturated Esters and Ketones
- A Frequency Domain Existence Proof of Single-Molecule Surface-Enhanced Raman Spectroscopy
- Total Synthesis and Structural Revision of the Marine Macrolide Neopeltolide
- Highly Diastereo- and Enantioselective Additions of Homoenolates to Nitrones Catalyzed by N-Heterocyclic Carbenes
- Direct Amination of Homoenolates Catalyzed by N-Heterocyclic Carbenes
- Heterogeneous Ozone Oxidation Reactions of 1-Pentene, Cyclopentene, Cyclohexene, and a Menthenol Derivative Studied by Sum Frequency Generation
- Catalytic, Three-Component Assembly Reaction for the Synthesis of Pyrrolidines
- Formation of Aza-ortho-quinone Methides Under Room Temperature Conditions: Cs2CO3 Effect
- Two Azolium Rings are Better than One: A Strategy for Controlling Catenation and Morphology in Zn and Cu Metal-Organic Frameworks
- N-Heterocyclic Carbene-Like Catalysis by a Metal-Organic Framework (MOF) Material
- Synthesis and Gas Sorption Properties of a Metal-Azolium Framework (MAF) Material
- Catalytic Conjugate Additions of Carbonyl Anions under Neutral Aqueous Conditions
- Direct Nucleophilic Acylation of Nitroalkenes Promoted by a Fluoride Anion/Thiourea Combination
- Hydroacylation of Activated Ketones Catalyzed by N-Heterocyclic Carbenes
- Radical coupling of β-keto esters and amides promoted by Brønsted/Lewis acids
- Stereoselective Lewis Acid-Catalyzed α-Acylvinyl Additions
- Synthesis of Tertiary β-Hydroxy Amides by Enolate Additions to Acylsilanes
- Anion Chelation by Amino Acid-Functionalized Fused Quartz/Water Interfaces Studied by Nonlinear Optics
- Nucleophilic Acylation of o-Quinone Methides: An Umpolung Strategy for the Synthesis of α-Aryl Ketones and Benzofurans
- Catalytic Enantioselective Synthesis of Flavanones and Chromanones
- Highly Stereoselective Formal [3+3] Cycloaddition of Enals and Azomethine Imines Catalyzed by N-Heterocyclic Carbenes
- Enantioselective Synthesis of α,α-Disubstituted Cyclopentenes by an N-Heterocyclic Carbene-Catalyzed Desymmetrization of 1,3-Diketones
- N-Heterocyclic Carbene-Catalyzed Conjugate Additions of Alcohols
- Single-Molecule Surface-Enhanced Raman Spectroscopy of Crystal Violet Isotopologues: Theory and Experiment
- Urea Metal–Organic Frameworks as Effective and Size Selective Hydrogen–Bond Catalysts
- A Dual Lewis Base Activation Strategy for Enantioselective Carbene-Catalyzed Annulations
- Asymmetric Homoenolate Additions to Acyl Phosphonates through Rational Design of a Tailored N-Heterocyclic Carbene Catalyst
- Enantioselective Annulations for Dihydroquinolones by in Situ Generation of Azolium Enolates
- Jammed Acid-Base Reactions at Interfaces
- Single-electron carbene catalysis in redox processes
- Amide Enolate Additions to Acylsilanes: In Situ Generation of Unusual and Stereoselective Homoenolate Equivalents
- Total Synthesis and Structure-Activity Investigation of the Marine Natural Product Neopeltolide
- N-Heterocyclic Carbene-Catalyzed Enantioselective Mannich Reactions with α-Aryloxyacetaldehydes
- Discovery of Highly Potent Serotonin 5-HT2 Receptor Agonists Inspired by Heteroyohimbine Natural Products
- Enantioselective Synthesis of Substituted Indanones from Silyloxyallenes
- Cooperative N-Heterocyclic Carbene/Lewis Acid Catalysis for Highly Stereoselective Annulation Reactions with Homoenlates
- Copper-Promoted N-Arylations of Cyclic Imides within Six-Membered Rings: A Facile Route to Arylene-Based Organic Materials
- Thiazolium-Catalyzed Additions of Acylsilanes: A General Strategy for Acyl Anion Addition Reactions
- Synthesis of Cyclohexanones by a Tandem Photocatalyzed Annulation
- Catalytic Multicomponent Reactions for the Synthesis of N-Aryl Trisubstituted Pyrroles
- Microwave-Assisted Piloty–Robinson Synthesis of 3,4-Disubstitued Pyrroles
- Assembly of Four Diverse Heterocyclic Libraries Enabled by Prins Cyclization, Au-Catalyzed Enyne Cycloisomerization, and Automated Amide Synthesis
- Insights into Heterogeneous Atmospheric Oxidation Chemistry: Development of a Tailor-Made Synthetic Model for Studying Tropospheric Surface Chemistry
- Environmental Biogeochemistry Studied by Second Harmonic Generation: A Look at the Agricultural Antibiotic Oxytetracycline
- Single-Molecule Tip-Enhanced Raman Spectroscopy
- Concise Syntheses of the Abyssinones and Discovery of New Inhibitors of Prostate Cancer and MMP-2 Expression
- Catalytic Additions of Acylsilanes to Imines: An Acyl Anion Strategy for the Direct Synthesis of α-Amino Ketones
- Efficient Synthesis of Acylsilanes Using Morpholine Amides
- Catalytic Multicomponent Synthesis of Highly Substituted Pyrroles Utilizing a One-Pot Sila-Stetter/Paal–Knorr Strategy
- Stereoselective Synthesis of Tetrahydropyran-4-ones from Dioxinones Catalyzed by Scandium(III) Triflate
- Conversion of α,β-Unsaturated Aldehydes into Saturated Esters: An Umpolung Reaction Catalyzed by Nucleophilic Carbenes
- Stereoselective Synthesis of α-Silylamines by the Direct Addition of Silyl Anions to Activated Imines
- Lewis Base-Catalyzed Additions of Alkynes Using Trialkoxysilylalkynes
- Enantioselective MSPV Reduction of Ketimines Using 2-Propanol and (BINOL)AlIII
- Tandem Oxidation of Allylic and Benzylic Alcohols to Esters Catalyzed by N-Heterocyclic Carbenes
- N-Heterocyclic Carbene-Initiated α-Acylvinyl Anion Reactivity: Additions of α-Hydroxypropargylsilanes to Aldehydes
- NHC-Catalyzed/Titanium(IV)–Mediated Highly Diastereo- and Enantioselective Dimerization of Enals
- Highly Stereoselective Brønsted Acid Catalyzed Synthesis of Spirooxindole Pyrans
- A Biomimetic Strategy to Access the Silybins: Total Synthesis of (—)-Isosilybin A
- NHC-Catalyzed Reactions of Aryloxyacetaldehydes: A Domino Elimination/Conjugate Addition/Acylation Process for the Synthesis of Substituted Coumarins
- Single-Flask Synthesis of N-Acylated Indoles by Catalytic Dehydrogenative Coupling with Primary Alcohols
- Impact of Solvent Polarity on N-Heterocyclic Carbene-Catalyzed β-Protonations of Homoenolate Equivalents
- Catalytic Asymmetric Alkylation of Substituted Isoflavanones
- Catalytic Enantioselective Total Syntheses of Bakkenolides I, J, and S: Application of a Carbene-Catalyzed Desymmetrization
- Catalytic, Enantioselective β-Protonation through a Cooperative Activation Strategy
- Combined Effects of Carbonate and Soft-Segment Molecular Structures on the Nanophase Separation and Properties of Segmented Polyhydroxyurethane
- A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family
- Non-Isocyanate Thermoplastic Polyhydroxyurethane Elastomers via Cyclic Carbonate Aminolysis: Critical Role of Hydroxyl Groups in Controlling Nanophase Separation
- Lewis Acid-Catalyzed Conjugate Additions of Silyloxyallenes: A Selective Solution to the Intermolecular Rauhut−Currier Problem
- Highly Selective α-Acylvinyl Anion Additions to Imines
- An Unusual Dianion Equivalent from Acylsilanes for the Synthesis of Substituted β-Keto Esters
- Cooperative Lewis Acid/N-Heterocyclic Carbene Catalysis
- Lewis Base-Promoted Carbon-Carbon sp3–sp3 Coupling Reactions of α-Silyl Silylethers
- A facile synthesis of UiO-66, UiO-67 and their derivatives
- A Mixed Dicarboxylate Strut Approach To Enhancing Catalytic Activity Of A De Novo Urea Derivative Of Metal-Organic Framework Uio-67
- A Zwitterionic Metal-Organic Framework with Free Carboxylic Acid Sites that Exhibits Enhanced Hydrogen Adsorption Energies
- A Concise Enantioselective Synthesis and Cytotoxic Evaluation of the Anticancer Rotenoid Deguelin Enabled by a Tandem Knoevenagel/Conjugate Addition/Decarboxylation Sequence
- A Cooperative N-Heterocyclic Carbene/Palladium Catalysis System
- Functionalized cyclopentenes through a tandem NHC-catalyzed dynamic kinetic resolution and ambient temperature decarboxylation: mechanistic insight and synthetic application
- N-Heterocyclic Carbene-Catalyzed Enantioselective Annulations: A Dual Activation Strategy for a Formal [4+2] Addition for Dihydrocoumarins
- A continuing challenge: N-heterocyclic carbene-catalyzed syntheses of γ-butyrolactones
- Calcium(II)-catalyzed enantioselective conjugate additions of amines
- Triethoxysilane (Update)
- Amide Bonds Made in Reverse
- Cooperative Catalysis by Carbenes and Lewis Acids in a Highly Stereoselective Route to γ-Lactams
- Synthesis of Acylsilanes from Morpholine Amides. Synthesis of 1-(Dimethyl(Phenyl)silyl)propan-1-one
- A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated kinase kinase 4
- A Highly Diastereoselective, Catalytic Three-Component Assembly Reaction for the Synthesis of Spiropyrrolidinyloxindoles
- Metal-Organic Framework Materials as Catalysts
- Discovering New Reactions with N-Heterocyclic Carbene Catalysis
- Synthesis of Enantioenriched α,α-Disubstituted Cyclopentenes Catalyzed by N-Heterocyclic Carbenes
- Highly Enantioselective Intramolecular Michael Reaction Catalyzed by N-Heterocyclic Carbenes
- Catalytic Enantioselective α-Acylvinyl Addition Reactions of Silyloxyallenes
- Pyrrolidinyl-Spirooxindole Natural Products as Inspirations for the Development of Potential Therapeutic Agents
- Targeting the tamoxifen receptor within sodium channels to block osteoarthritic pain
- Highly Stereoselective Synthesis of Substituted γ-Lactams From Acylsilanes
- A Cooperative Hydrogen Bond Donor/Brønsted Acid System for the Enantioselective Synthesis of Tetrahydropyrans
- Carbene‐Catalyzed Enantioselective Decarboxylative Annulations to Access Dihydrobenzoxazinones and Quinolones
- Synthesis and Evaluation of Azolium-Based Halogen Bond Donors
- Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors
- Combined Photoredox and Carbene Catalysis for the Synthesis of Ketones from Carboxylic Acids
- A Sequential Umpolung/Enzymatic Dynamic Kinetic Resolution Strategy for the Synthesis of γ-Lactones
- Targeted Covalent Inhibition of Telomerase
- A Concise, Enantioselective Approach for the Synthesis of Yohimbine Alkaloids
- N-Heterocyclic Carbene-Catalyzed Oxidation of Unactivated Aldehydes to Esters
- NHC-Catalyzed Formal [2+2] Annulations of Allenoates for the Synthesis of Substituted Oxetanes
- Development of Ferrocene-Based Planar Chiral Imidazopyridinium Salts for Catalysis
- Intermolecular Reductive Couplings of Arylidene Malonates via Lewis Acid/Photoredox Cooperative Catalysis
- An Enantioselective Cross-Dehydrogenative Coupling Catalysis Approach to Tetrahydropyrans
- Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization
- Enantioselective Synthesis of α-Amidoboronates Catalyzed by Planar-Chiral NHC-Cu(I) Complexes
- Reductive Annulations of Arylidene Malonates With Unsaturated Electrophiles Using Photoredox/Lewis Acid Cooperative Catalysis
- Mechanism and Origins of Selectivity in the Enantioselective oxa-Pictet-Spengler Reaction: A Cooperative Catalytic Complex from a Hydrogen Bond Donor and Chiral Phosphoric Acid
- Precision therapeutic targeting of human cancer cell motility
- Computational planning of the synthesis of complex natural products
- N-Heterocyclic Carbene-Promoted Rauhut-Currier Reactions between Vinyl Sulfones and α,β-Unsaturated Aldehydes
- N-Heterocyclic Carbene-Catalyzed Rearrangements of Vinyl Sulfones
- High-throughput photocapture approach for reaction discovery
- Non-classical MEKs: A review of MEK3-7 inhibitors
- Protonation of Homoenolate Equivalents Generated by N-Heterocyclic Carbenes
- Intermolecular Crossed-Acyloin Reactions by Fluoride-Promoted Additions of O-Silyl Thiazolium Carbinols
- N-Heterocyclic Carbene-Catalyzed Aldol Desymmetrizations
- Acyloin Coupling Reactions
- Carbene Catalysis: Beyond the Benzoin and Stetter Reactions
- Design, Syntheses and Studies of New Antibacterial, Antifungal and Antiviral Agents
- Studies on the Synthesis of Bafilomycin A: Stereochemical Aspects of the Fragment Assembly Aldol Reaction for Construction of the C(13)-C(25) Segment
- Total Synthesis of (-)-Bafilomycin A1
- Remarkably Stable Tetrahedral Intermediates: Carbinols from Nucleophilic Additions to N-Acylpyrroles
- Enantioselective Indole Friedel-Crafts Alkylations Catalyzed by Bis(oxazolinyl)pyridine-Scandium(III) Triflate Complexes
- Enantioselective Friedel-Crafts Alkylations Catalyzed by Bis(oxazolinyl)pyridine-Scandium(III) Triflate Complexes
- Studies on the Synthesis of Apoptolidin A. 1. Synthesis of the C(1)-C(11) Fragment
- Applications of Zr-Catalyzed Carbomagnesation and Mo-Catalyzed Macrocyclic Ring Closing Metathesis in Asymmetric Synthesis: Enantioselective Synthesis of Sch38516 (Fluvirucin B1)
- Enantioselective Copper-Catalyzed Borylative Amidation of Allenes
- Tris(dimethylamino)sulfonium Difluorotrimethylsilicate, a Mild Reagent for the Removal of Silicon Protecting Groups
- Vinyl Sulfonate Esters and Vinyl Sulfonamides: Potent, Irreversible Inhibitors of Cysteine Proteases
- Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors
- Total Synthesis of (–)-Bafilomycin A1: Application of Diastereoselective Crotylboration and Methyl Ketone Aldol Reactions
- Enantioselective and Diastereoselective Mukaiyama-Michael Reactions Catalyzed by Bis(oxazoline) Copper(II) Complexes
- Synthesis of (–)-Epibatidine
- An NMR Method for Assigning Relative Stereochemistry to β-Hydroxy Ketones Deriving from Aldol Reactions of Methyl Ketones
- Photoinduced Acylations Via Azolium-Promoted Intermolecular Hydrogen Atom Transfer
- Rational Design of Highly Potent and Selective Covalent MAP2K7 Inhibitors
- Acyl Azolium–Photoredox-Enabled Synthesis of β-Keto Sulfides
- Visible light-induced coupling of carboxylic acids with alcohols/amines via a phosphorous linchpin strategy
- Photocatalyzed Direct α-Alkylation of Esters Using Styrenes
- Light-Driven Carbene Catalysis for the Synthesis of Aliphatic and α-Amino Ketones
- Photocatalytic acyl azolium-promoted alkoxycarbonylation of trifluoroborates